https://ijcbr.com/index.php/ijcbr <div id="embase-announcement-wrapper"> <div class="card-container"> <div class="card"> <div class="logo-section"><img src="https://pharmacologymentor.com/wp-content/uploads/2026/01/logo-embase.png" alt="Elsevier Embase Logo" /></div> <span class="badge">Major Achievement</span> <h2>Global Recognition</h2> <p>We are delighted to announce that our journal is now officially <strong>indexed and induced</strong> within the <strong>Elsevier EMBASE</strong> database. This milestone reflects our commitment to high-quality clinical research and global accessibility.</p> <div class="attachment-box"> <div class="file-info"> <div class="file-icon"> </div> <div><span class="file-name">Embase_Indexing_Proof.png</span> <span class="file-size">Indexing Verification • Image</span></div> </div> <a class="download-btn" href="https://pharmacologymentor.com/wp-content/uploads/2026/01/Screenshot-2026-01-06-at-6.49.41-PM.png" target="_blank" rel="noopener">View Proof</a></div> </div> </div> </div> <div style="font-family: 'Segoe UI', Arial, sans-serif; max-width: 800px; margin: 0 auto; color: #333; line-height: 1.6;"> <div style="text-align: center; background-color: #f8f9fa; padding: 15px; border-bottom: 2px solid #0056b3; margin-bottom: 20px;"> <p style="margin: 0; font-size: 1.1em;"><strong>ISSN:</strong> 2395-0471 (Online) | <strong>ISSN:</strong> 2521-0394 (Print)</p> </div> <div style="text-align: center; margin-bottom: 30px;"> <p style="color: #555; font-size: 0.9em; margin-bottom: 15px;"><strong>Indexed in major databases (click logo to view):</strong></p> <div style="display: flex; flex-wrap: wrap; justify-content: center; align-items: center; gap: 20px;"><a href="https://www.base-search.net/Search/Results?q=dccoll:ftsumathipubl&amp;refid=dcrecen" target="_blank" rel="noopener"> <img style="height: 35px; width: auto;" src="https://www.sumathipublications.com/public/site/images/admin/base.png" alt="BASE" /> </a> <a href="https://scholar.google.co.in/scholar?start=0&amp;q=2395-0471&amp;hl=en&amp;as_sdt=0,5" target="_blank" rel="noopener"> <img style="height: 28px; width: auto;" src="https://www.sumathipublications.com/public/site/images/admin/GoogleScholar1.png" alt="Google Scholar" /> </a> <a href="http://www.worldcat.org/search?q=ijcbr&amp;qt=results_page" target="_blank" rel="noopener"> <img style="height: 32px; width: auto;" src="https://www.sumathipublications.com/public/site/images/admin/logo_wcmasthead_en1.png" alt="WorldCat" /> </a> <a href="http://index.pkp.sfu.ca/index.php/browse/index/4035" target="_blank" rel="noopener"> <img style="height: 35px; width: auto;" src="https://www.sumathipublications.com/public/site/images/admin/pkp-index-301.png" alt="PKP Index" /> </a> <a href="https://v2.sherpa.ac.uk/id/publication/30542" target="_blank" rel="noopener"> <img style="height: 35px; width: auto;" src="https://www.sumathipublications.com/public/site/images/admin/sherparomeo-home.jpg" alt="Sherpa Romeo" /> </a> <a href="http://imsear.searo.who.int/handle/123456789/170455?subject_page=1" target="_blank" rel="noopener"> <img style="height: 30px; width: auto;" src="https://www.sumathipublications.com/public/site/images/admin/rsz_21rsz_1rsz_imsear.png" alt="IMSEAR" /> </a></div> </div> <hr style="border: 0; border-top: 1px solid #eee; margin: 20px 0;" /> <h3 style="color: #0056b3; border-left: 4px solid #0056b3; padding-left: 10px;">About the Journal</h3> <p>The <em>International Journal of Clinical and Biomedical Research (IJCBR)</em> is an open-access, peer-reviewed, international journal (Online &amp; Print). Our primary objective is to publish high-quality research and applications across all branches of <strong>Biomedical and Health Sciences</strong>, including:</p> <ul style="display: grid; grid-template-columns: repeat(auto-fit, minmax(200px, 1fr)); gap: 5px; background: #f9f9f9; padding: 15px 15px 15px 35px; border-radius: 5px;"> <li>Biology</li> <li>Dentistry</li> <li>Medical Education</li> <li>Physiotherapy</li> <li>Pharmacy</li> <li>Nursing</li> </ul> <h3 style="color: #0056b3; border-left: 4px solid #0056b3; padding-left: 10px; margin-top: 30px;">Submission &amp; Review Process</h3> <p>Submitted manuscripts must be written in technical English suitable for scientific publication. All submissions must be <strong>original articles</strong> that have not been published elsewhere and are not currently under consideration by other journals.</p> <p><strong>Peer Review:</strong> All articles will be peer-reviewed by subject matter experts. We strive to complete the review process and communicate the decision to the corresponding author within <strong>3 weeks</strong> of receipt.</p> <div style="background-color: #fff3cd; border: 1px solid #ffeeba; padding: 15px; border-radius: 5px; margin: 20px 0;"><strong style="display: block; margin-bottom: 10px; color: #856404;">Accepted Manuscript Types:</strong> <ul style="margin: 0; padding-left: 20px; column-count: 2; column-gap: 20px;"> <li>Original research articles</li> <li>Reviews</li> <li>Case reports</li> <li>Short communications</li> <li>Letters to the Editor</li> <li>Discussion papers</li> <li>Clinical Experience</li> <li>Clinicopathological correlation</li> <li>Book reviews</li> <li>"How to do it" (New methods/procedures)</li> </ul> </div> <p>Papers should be submitted electronically via the journal's website. The Editorial Board is dedicated to maintaining high quality and ensuring the journal is updated in various indexing bodies regularly. We welcome your next submission.</p> <div style="background-color: #e9ecef; padding: 15px; border-radius: 5px; text-align: center; margin-top: 20px;"><strong>Contact Us</strong><br />For further information, please email:<br /><a style="color: #0056b3; text-decoration: none; font-weight: bold;" href="mailto:editor.ijcbr@gmail.com">Editor</a> | <a style="color: #0056b3; text-decoration: none; font-weight: bold;" href="mailto:journaloffice@sumathipublications.com">Journal Office</a></div> <p style="margin-top: 30px; font-style: italic;">Kind regards,<br /><strong>IJCBR Editorial Team</strong></p> </div> Sumathi Publications en-US International Journal of Clinical and Biomedical Research 2521-0394 <p>The journal <strong>allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions</strong>.</p> https://ijcbr.com/index.php/ijcbr/article/view/419 <p>Oxidative stress, characterized by an imbalance between the production of the reactive oxygen species (ROS) and the ability of the antioxidant defense systems. It is crucial to the pathophysiology of infertile women, deleterious impacts through the oocyte maturation, ovulatory functions, associated with reproductive disorders as polycystic ovary syndrome (PCOS) and endometriosis. Mitochondria of oocytes and granulosa cells are the leading sources of ROS whose generation is further worsened by ageing, obesity, as well as environmental assaults. Although physiological levels of ROS are necessary to normal follicular growth and ovulation, excessive levels of ROS cause oocyte DNA breakage, meiotic spindle deregulation, and embryonic in survival. The inherent antioxidant enzymes which as superoxide dismutase (SOD) and glutathione, give the cellular systems partial protection against oxidative damage, however significant and the exogenous antioxidant supplementation such as vitamins C and E, coenzyme Q10, N-acetyl cysteine as well as Melatonin have shown an encouraging result in randomized controlled trials (RCTs) and meta-analyses. Clinical evidence shows that there are better ovarian responsiveness and better oocyte yield and better pregnancy rates in assisted reproductive technologies (ART) especially in women with advanced ovarian age or PCOS. A Cochrane systematic review found a moderate relationship between antioxidant use and increased rates of live births, but the evidence quality was overall low because of the study heterogeneity. Notably, antioxidant interventions were generally well-tolerated and portable with minimal side effects. Future studies ought to focus on more rigorously constructed, high quality, RCTs that are targeted at clinically meaningful end point outcomes like live birth rates as well as consider adjunct parameters of sperm DNA fragmentation, which modifies female reproductive outcomes indirectly. Combination of personalized antioxidant treatment and specific lifestyle changes has a significant therapeutic potential for the female reproductive health and optimizing fertility.</p> Dr Shaily Sengar Dr Deepali Jain Dr Rekha Gurjar Copyright (c) 2026 Dr Shaily Sengar, Dr Deepali Jain, Dr Rekha Gurjar http://creativecommons.org/licenses/by-nc-sa/4.0 2026-01-10 2026-01-10