RECURRENT PREGNANCY LOSS AND ASSOCIATION OF MTHFR, PAI-1 AND ACE GENE POLYMORPHISMS IN WOMEN

Pandey, Snehlata; Pandey, Archana; Chauhan, U.K.; Tripathi, Arvind; Tripathi, Jitendra; Dubey, Sanjeev; Deo Saket, Rishabh

IJCBR|ISSN: 2521-0394|eISSN: 2395-0471Open Access (CC BY-NC-SA 4.0)

IJCBRInternational Journal of Clinical and Biomedical Research

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International Journal of Clinical and Biomedical Research is an open-access, peer-reviewed journal published by Sumathi Publications, Vijayapura, Karnataka, India. Articles are licensed under CC BY-NC-SA 4.0 unless stated otherwise.

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eISSN 2395-0471 · ISSN 2521-0394

RECURRENT PREGNANCY LOSS AND ASSOCIATION OF MTHFR, PAI-1 AND ACE GENE POLYMORPHISMS IN WOMEN | IJCBR

International Journal of Clinical and Biomedical Research / Volume 1, Issue 4; October 2015

Review ArticlesPeer-reviewedOpen Access · CC BY-NC-SA 4.0

RECURRENT PREGNANCY LOSS AND ASSOCIATION OF MTHFR, PAI-1 AND ACE GENE POLYMORPHISMS IN WOMEN

Snehlata Pandey¹, Archana Pandey², U.K. Chauhan³, Arvind Tripathi⁴, Jitendra Tripathi⁵, Sanjeev Dubey⁶, Rishabh Deo Saket⁷

¹ — (corresponding author)
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Published 2015-10-28 · pp. 50-55

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Abstract

Recurrent pregnancy loss (RPL) is a significant clinical problem that may occur before the 20^th week of gestation. There is no general consensus on how many consecutive abortions are considered as RPL. The goal of this study is to investigate the correlation between recurrent miscarriage (RM) and common polymorphisms in angiotensin-converting enzyme (ACE), plasminogen activator inhibitor 1 (PAI-1) and Methylenetetrahydrofolate Reductase (MTHFR) genes among women experiencing RM. The literature existing in different population was searched and based on these finding we conclude that polymorphism in either one of these genes may increase chances of miscarriage.

KEYWORDS: Polymorphism; Recurrent pregnancy; Plasminogen activator inhibitor 1.

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History

Received: 2018-02-08
Published: 2015-10-28

How to cite

Pandey S, Pandey A, Chauhan U, Tripathi A, Tripathi J, Dubey S, Deo Saket R. RECURRENT PREGNANCY LOSS AND ASSOCIATION OF MTHFR, PAI-1 AND ACE GENE POLYMORPHISMS IN WOMEN. IJCBR. 2015;1(4):50-55.